BOURNE, Gregory,CHENG, XiaoLi,FREDERICK, Brian Troy,ZHANG, Jie,PATEL, Dinesh V.,LIU, David,BHANDARI, Ashok
申请号：
PE2018000053
公开号：
PE20185712A1
申请日:
2016.07.15
申请国别(地区):
PE
年份:
2018
代理人:
摘要：
The substance refers to the PFOS inhibitor contained in the receptor with a spacing of 23, including any series of amino acids with ID numbers of 365-370 and 857-1029, and the preferred compounds are: [palmitate] - [isosaccharide] - [pag4] - [pen] - [pen] - ntwq - [pen] - [PE [4 - (2-nal] - [AIB] - [Lys (AC)] - nnnnnnnh2, etc. It also mentions a pharmacological synthesis, which includes a capsicum inhibitor and a carrier, precursor or diluent, pharmacologically acceptable, pharmacologically acceptable, and in addition, this composition includes a complete coating, and the present invention is used for ulcerative colitis, Crohn's disease, etc.Se refiere a inhibidores peptidicos del receptor de interleucina 23 y comprende una secuencia de aminoacidos de cualquiera de las SEC ID N°: 365-370, 857-1029 y tiene como compuesto preferidos: [Palm]-[isoGlu]-[PEG4]-[Pen]-NTWQ-[Pen]-[Phe[4-(2-aminoeotxi)]-[2-Nal]-[Aib]-[Lys(Ac)]-NNNH2； entre otros. Tambien se refiere a una composicion farmaceutica que comprende el inhibidor peptidico y un portador, excipiente o diluyente farmaceuticamente aceptables y ademas esta composicion comprende un recubrimiento enterico, la presente invencion es util para colitis ulcerosa, enfermedad de Crohn, entre otros.
