Limited Liability Company "Cardiosystempharma" (LLC "CSP")
发明人:
申请号：
EP15819585.9
公开号：
EP3167874B1
申请日:
2015.06.05
申请国别(地区):
EP
年份:
2018
代理人:
摘要：
This invention relates to medicine, more specifically, to cardiac surgery, and may be used for protecting the heart from ischemia when administering cardioplegia in normothermia or hypothermia. The general-purpose cardioplegic solution contains pharmaceutically acceptable potassium ions； magnesium ions； a base and an acid providing a pH buffer in a range of 7.1-8.9； a diuretic providing osmolality in a range of 275-460 mOsmol/kg. Said solution is used for cardiac protection in cardiopulmonary bypass, as well as for achieving asystole and maintaining the achieved asystole. The procedure for administering the general-purpose cardioplegic solution involves maintaining the achieved asystole by decreasing the flow rate of starting components of said solution relative to the flow rate of autoblood thus decreasing the solution to autoblood ratio.
