KOTIAN, PRAVIN L.,BABU, YARLAGADDA S.,KUMAR, V. SATISH,ZHANG, WEIHE,LU, PENG-CHENG,RAMAN, KRISHNAN
申请号:
CA3066164
公开号:
CA3066164A1
申请日:
2018.06.14
申请国别(地区):
CA
年份:
2018
代理人:
摘要:
Disclosed are compounds of formula (I), (II), (III), and (IV), andpharmaceutically acceptable salts thereof. The compoundsare inhibitors of ALK2 kinase. Also provided are pharmaceutical compositionscomprising a compound of formula (I), (II),(III), or (IV), or pharmaceutically acceptable salt thereof, and methodsinvolving use of the compounds or pharmaceutically acceptablesalts thereof and compositions in the treatment and prevention of variousdiseases and conditions, such as fibrodysplasia ossificansprogressiva.