Eric S. EDWARDS,Evan T. EDWARDS,Mark J. LICATA,Paul F. MEYERS,Frank E. BLONDINO
申请号:
US16438203
公开号:
US20190290855A1
申请日:
2019.06.11
申请国别(地区):
US
年份:
2019
代理人:
摘要:
Medicament delivery devices for administration of opioid antagonists are described herein. In some embodiments, an apparatus includes a housing, a medicament container disposed within the housing and an energy storage member disposed within the housing. The medicament container is filled with a naloxone composition that includes naloxone or salts thereof, a tonicity-adjusting agent, and a pH-adjusting agent, whereby the osmolality of the naloxone composition ranges from about 250-350 mOsm and the pH ranges from about 3-5. The energy storage member is configured to produce a force to deliver the naloxone composition.