POLYPRENYLATED PHLOROGLUCINOL COMPOUNDS AS POTENT P-GLYCOPROTEIN INDUCERS

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专利权人:

COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH

发明人:

BHARATE, SANDIP,KUMAR, AJAY,BHARATE, JAIDEEP,JOSHI, PRASHANT,WANI, ABUBAKAR,MUDUDUDDLA, RAMESH,SHARMA, ROHIT,VISHWAKARMA, RAM

申请号：

CA2962725

公开号：

CA2962725A1

申请日:

2015.07.20

申请国别(地区):

CA

年份:

2016

代理人:

摘要：

The present invention relates to the polyprenylated phloroglucinol compounds of formulae I and II. The present invention also provides synthesis and p-glycoprotein induction activity of the alkyl- and acyl- polyprenylated phloroglucinol compounds. Further, use of the compounds as p-glycoprotein inducers and methods of treatment of Alzheimers disease using compounds of the invention are also provided.

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