מלח המיסולפט של n – (r9, s6, s5) – 5 אמינו – 6 – (2, 3 – דיפלואורופניל) – 6, 7, 8, 9, – טטראהידרו – h5 – ציקלוהפטא [b] פירידינ – 9 – איל – 4 – ( 2– אוקסו – 2, 3, דיהידרו – h1 – אימידאזו [5,4 –b] פירידינ– 1 – איל) פיפרידינ – 1 – קרבוקסילאט

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专利权人:

BRISTOL-MYERS SQUIBB COMPANY

发明人:

申请号：

IL23427214

公开号：

IL234272A

申请日:

2014.08.24

申请国别(地区):

IL

年份:

2018

代理人:

摘要：

Disclosed is a hemisulfate salt of Compound (I): and crystalline forms of the hemisulfate salt. Also disclosed are methods of using the hemisulfate salt of Compound (1) as a CGRP receptor antagonist, and pharmaceutical compositions comprising the hemisulfate salt of Compound (I). The hemisulfate salt of Compound (I) is useful in treating, preventing, or ameliorating disorders including migraine and other headaches, neurogenic vasodilation, neurogenic inflammation, thermal injury, circulatory shock, flushing associated with menopause, airway inflammatory diseases such as asthma, and chronic obstructive pulmonary disease (COPD).

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中国工程科技知识中心

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http://www.ckcest.cn/home/