Haresh Bhagat,Gerald D. Cagle,Francis X. Smith,Paul D. Hartung
申请号:
US15864679
公开号:
US10350309B2
申请日:
2018.01.08
申请国别(地区):
US
年份:
2019
代理人:
摘要:
The present invention relates to a process for preparing an ointment comprising subjecting a mixture of a fluorescent molecular rotor compound, mineral oil, and grinding media to ball milling agitation and combining this mixture with a hydrophobic vehicle for an ointment. The invention also relates to an ophthalmic formulation comprising a pharmaceutically acceptable carrier and a compound of the following structural Formula (I), or a pharmaceutically acceptable salt thereof:Values and preferred values of the variables in structural Formula (I) are described herein.