The present invention provides a device for delivering a predetermined amount of at least one substance to a body orifice of a subject； comprising: a. a container for containing said at least one substance； b. a delivery end for placement in proximity to said orifice, said delivery end being in fluid communication with said container； c. a valve mechanically connectable to said container, characterized by at least two configurations: (i) an ACTIVE CONFIGURATION in which said valve enables delivery of predetermined amount of said substance from said container to said body orifice via said delivery end； and, (ii) an INACTIVE CONFIGURATION, in which said valve prevents delivery of said predetermined amount of said substance from said container to said body orifice； d. a trigger mechanism adapted to reconfigure said valve from said INACTIVE CONFIGURATION to said ACTIVE CONFIGURATION, and vice versa； e. a fluid tight chamber.
