The present application relates to non-aqueous topical pharmaceutical formulations that are non-desquamating. The formulation includes an organic solvent having tissue penetration properties, an organic co-solvent, and a film forming agent. The formulation may further comprise an antimicrobial agent. [Selection] Figure 1本願は、非落屑性である非水性局所医薬製剤に関する。製剤は、組織浸透特性を有する有機溶媒、有機共溶媒及びフィルム形成剤を含む。製剤は、抗菌薬剤を更に含んでもよい。【選択図】図1