Pyrazolotriazines as inhibitors of nucleases

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专利权人:

发明人:

Jiri Damborsky,Fedor Nikulenkov,Alexandra Sisakova,Stepan Havel,Lumir Krejci,Benoit Carbain,Jan Brezovsky,Lukas Daniel,Kamil Paruch

申请号：

US15316764

公开号：

US09969741B2

申请日:

2015.06.17

申请国别(地区):

US

年份:

2018

代理人:

摘要：

The invention provides compounds represented by the structural formula (1):wherein R1, R2, R3 and R4 are as defined in the claims. The compounds are inhibitors of nucleases, and are useful in particular in a method of treatment and/or prevention of proliferative diseases, neurodegenerative diseases, and other genomic instability associated diseases.

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