A dispensing device for dispensing a clinical substance for dental or medical use, configured as either integrated into a handpiece for dental or medical use or adjacent to said handpiece. The dispensing device includes at least one exchangeable module comprising a primary fluid inlet, configured to be coupled to a primary fluid supply duct and a fluid outlet, configured to deliver fluid that can be loaded with a clinical substance, the exchangeable module comprising a chamber containing the substance to be dispensed in liquid, gel, or powder form, the chamber forming a substance reserve, such that when primary fluid circulates between inlet and outlet, the fluid can collect clinical substance.