PRYDE DAVID CAMERON,KOLHE PARAG ASHOK,PARSONS ERIN KRISTEN,BROWN ALAN DANIEL,STEAD DAVID ROBERT,THORN JENNIFER MARIE,MERSON JAMES RICHARD,GERVAIS DAVID P.,MCCLUSKIE MICHAEL JOHN,FINNEMAN JARI ILMARI,D
申请号：
NZ60381911
公开号：
NZ603819A
申请日:
2011.06.03
申请国别(地区):
NZ
年份:
2014
代理人:
摘要：
Disclosed is a hapten-carrier conjugate of formula III. The conjugate includes compounds such as trans-4-amino-N-(3-{ 5-[(2S)-1-methylpyrrolidin-2-yl]pyridin-3-yl} propyl)cyclohexanecarboxamide and 4-mercapto-N-[2-({ 5-[(2S)-1-methylpyrrolidin-2-yl]pyridin-3-yl} oxy)ethyl]butanamide which are conjugated to an optionally modified carrier protein selected from bacterial toxoids, immunogenic substances, viruses, virus-like particles, protein complexes, proteins, polypeptides, liposomes and immuno-stimulating complexes. The conjugates are useful for aiding smoking cessation in smokers.
