The method that this Hair Ming Department Off Yu System make 3, the 4- dichloro Iso thiazole carboxylic acids of tool formula (I), (I),Its characteristic what Will cyanides, carbon disulfide and Lv Yu System methods the mono- Bu Sudden anti-Should of Zhong Jin rows and obtain the 3 of following formula, 4- dichloro Iso thiazoles nitriles (II),The molten Elixirs Zheng Evaporated of Qi Department whats go out Come , With alcohol Erbium-doped He Qie Over Filter Hou Single From into the solution in what alcohol, and so hydrolyze in what The alcohol under , Yu Alkaline Strip parts in the bis- Bu Sudden of Hou Yu System methods and obtain the acid of tool formula (I).本發明係關於製造具式(I)之3,4-二氯異噻唑羧酸的方法, (I),其特徵在於將氰化物、二硫化碳及氯於製法之第一步驟中進行反應而得到下式之3,4-二氯異噻唑腈 (II),其係於溶劑蒸餾出來,與醇摻合且過濾後單離成於醇中之溶液,且然後於製法之第二步驟中,於鹼性條件下於該醇中水解而得到具式(I)之酸。
