Subbalakshmi Malladi;Hari Prasad Kokatla;Diptesh Sil;Sunil Abraham David;Lauren Miranda Fox
发明人:
Sunil Abraham David,Hari Prasad Kokatla,Diptesh Sil,Subbalakshmi Malladi,Lauren Miranda Fox
申请号：
US15106488
公开号：
US20160347715A1
申请日:
2014.12.19
申请国别(地区):
US
年份:
2016
代理人:
摘要：
Compounds described herein can be used for therapeutic purposes. The compounds can be TLR agonists, such as TLR8 agonists. The compounds can be included in pharmaceutical compositions and used for therapies were being a TLR8 agonist is useful. The pharmaceutical compositions can include any ingredients, such as carries, diluents, excipients, fillers or the like that are common in pharmaceutical compositions. The compounds can be those illustrated or described herein as well as derivative thereof, prodrug thereof, salt thereof, or stereoisomer thereof, or having any chirality at any chiral center, or tautomer, polymorph, solvate, or combinations thereof. As such, the compounds can be used as adjuvants in vaccines as well as for other therapeutic purposes described herein. The compounds can have any one of the formulae described herein or derivative thereof.
