An in vitro focused ultrasound treatment device for pelvic disease, relating to the technical field of high intensity focused ultrasound treatment, and being able to solve the problem of lower efficiency, effectiveness, and safety of existing ultrasound treatment for prostate disease. The in vitro focused ultrasound treatment device for pelvic disease comprises an ultrasound transducer (1) and a treatment bed (2)； a sounding surface (3) of the ultrasound transducer (1) is a spherical surface having a first notch (31), a second notch (32), and a third notch (33)； a spherical center surface of the spherical surface is a main spherical center surface (99)； the first notch (31) and the second notch (32) are located at two intersections of a diameter perpendicular to the main spherical center surface (99) and the spherical surface； the third notch (33) connects the first notch (31) with the second notch (32)； the sounding surface (3) is of an arc shape in a section parallel to the main spherical center surface (99)； the sounding surface (3) can reflect ultrasound； ultrasound generated by a sounding unit is focused on the spherical center of the sounding surface； The treatment bed (2) allows a person to lie on the back in lithotomy position, so that the pelvic cavity is located at the spherical center of the sounding surface (3), the two legs pass through the sounding surface (3) via the first notch (31) and the second notch (32), and the upper part of the torso passes through the sounding surface (3) via the third notch (33).
