Childrens Medical Center Corporation;Children's Medical Center Corporation
发明人:
Smith, Lois,Joyal, Jean-Sebastien
申请号：
AU2017221441
公开号：
AU2017221441A1
申请日:
2017.02.17
申请国别(地区):
AU
年份:
2018
代理人:
摘要：
The instant invention provides methods and compositions related to discovery of Free Fatty Acid Receptor 1 (FFA1) as a therapeutic target for treatment or prevention of diseases or disorders of neurons that are characterized by angiogenesis, or of vascular diseases of the eye, retinal degeneration and/or tumors more generally. Therapeutic and/or prophylactic uses and compositions of known FFA1 inhibitors, including small molecules and nucleic acid agents, are described. Methods for identification of novel FFA1 inhibitors are also provided.
