An integrated guidewire includes a wire and a flexibletube. The wire is sized and shaped to move in an anatomicalmaterial transportation system of a patient. The flexibletube is sized and shaped to move in the anatomical materialtransportation system, having proximal and distal ends, theproximal-end is coupled to a device external to the patient,the flexible tube is configured to transfer fluids betweenthe distal-end and the device, and the wire and the flexibletube are intertwined with respect to one another.