GENENTECH, INC.; INC.;GENENTECH;F. HOFFMANN LA-ROCHE AG
发明人:
NILE, Aaron, Hugh,ZHANG, Yingnan,ZHOU, Lijuan,HANNOUSH, Rami
申请号：
USUS2017/050841
公开号：
WO2018/049275A1
申请日:
2017.09.08
申请国别(地区):
US
年份:
2018
代理人:
摘要：
Provided are ligands comprising a non-naturally occurring peptide that binds a cysteine rich domain (CRD) of the Frizzled7 (FZD7) receptor. Additionally, provided are therapeutic methods of using such ligands, as well as compositions comprising such ligands.L'invention concerne des ligands comprenant un peptide d'origine non naturelle qui se lie à un domaine riche en cystéine (CRD) du récepteur Frizzled7 (FZD7). De plus, l'invention concerne des méthodes thérapeutiques d'utilisation de tels ligands, ainsi que des compositions comprenant de tels ligands.
