The present invention relates to a needleless drug-injecting system and a drug-injecting method thereof, wherein the needleless drug-injecting system comprises a controlling device and a needleless drug-injecting device. By using the needleless drug-injecting system and the drug-injecting method, a user is able to individually set a variety of parameters comprising dose of fluid drug, shooting air pressure of fluid drug, flow rate of air, quantity of single shot, frequency of continuous shot, and interval of the frequency of continuous shot according to different fluid drug. Thus, after setting the parameters, the fluid drug can be injected into the dermis layer of the face skin of the human when the user using this needleless drug-injecting system to inject any one fluid drug to a human face, therefore the fluid drug would be absorbed by the face skin without hearting the human face.本發明係關於一種無針型注射系統及其注射方法,其中,該無針型注射系統係包括一控制裝置與一無針型注射裝置;並且,透過該無針型注射系統及其注射方法,使用者可以根據不同流體藥物之分子量而自行設定各種參數,該些參數包括:流體藥物使用劑量、流體藥物射擊氣壓、氣體流量、單次射擊量、連續射擊次數、以及連續射擊次數之間隔時間;如此,經過該些參數之設定後,當使用者使用該無針型注射系統將一流體藥物注入一注射目標物(例如人的臉部皮膚)之後,可以保證該流體藥物在不傷害人的臉部皮膚的前提下,注入至皮膚的真皮層,進而能夠加速皮膚對於該流體藥物之吸收。