Hemminki, Akseli,Kanerva, Anna,Cerullo, Vincenzo,Pesonen, Sari
申请号：
AU2009332883
公开号：
AU2009332883B2
申请日:
2009.12.21
申请国别(地区):
AU
年份:
2015
代理人:
摘要：
The present invention relates to the fields of life sciences and medicine. Specifically, the invention relates to cancer therapies. More specifically, the present invention relates to oncolytic adenoviral vectors and cells and pharmaceutical compositions comprising said vectors. The present invention also relates to a use of said vectors in the manufacture of a medicament for treating cancer in a subject and a method of treating cancer in a subject. Furthermore, the present invention relates to methods of producing GM-CSF in a cell and increasing tumor specific immune response in a subject, as well as uses of the oncolytic adenoviral vector of the invention for producing GM-CSF in a cell and increasing tumor specific immune response in a subject.
