UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION
发明人:
RUSSELL, DAVID W.,HIRATA, ROLI K.
申请号：
CA2833173
公开号：
CA2833173A1
申请日:
2012.04.18
申请国别(地区):
CA
年份:
2012
代理人:
摘要：
The invention provides isolated primate cells preferably human cells that comprise a genetically engineered disruption in a beta-2 microglobulin (B2M) gene, which results in deficiency in MHC class I expression and function. Also provided are the method of using the cells for transplantation and treating a disease condition.
