A high-voltage protection device for an ionic wind purifier is described, which includes a micro switch (1) and a contact point (2) matching with the micro switch (1). The micro switch (1) and the contact point (2) are connected in series on a main circuit. Either the micro switch (1) or the contact point (2) is located on an inner side of a door cover (2) of the ionic wind purifier and the other one is located on a contact part of a main body and the door cover (3). The high-voltage protection device can automatically cut off a power source when a door of the ionic wind purifier is opened, so as to ensure the safety of a user. An ionic wind purifier including the high-voltage protection device is also described.
