NISHINO, TAITO,MIYAJI, KATSUAKI,IWAMOTO, SHUNSUKE,MIKASHIMA, TAKUMI,SARUHASHI, KOICHIRO,KISHIKAWA, YO
申请号:
MYPI 2013001987
公开号:
MY165634A
申请日:
2011.12.01
申请国别(地区):
MY
年份:
2018
代理人:
摘要:
NOVEL THERAPEUTIC AGENTS FOR MYELOMA ARE PROVIDED. A THERAPEUTIC AGENT FOR MULTIPLE MYELOMA CONTAINING A PYRAZOLE COMPOUND REPRESENTED BY THE FORMULA (1): WHEREIN R1 IS C1 -C6 ALKYL, C1 -C6 ALKYL SUBSTITUTED WITH R17, CI -06 HALOALKYL, PHENYL, PHENYL SUBSTITUTED WITH A R’ S OR THE LIKE, R2 IS A HYDROGEN ATOM, CI -C6 ALKYL, PHENYL OR PHENYL OPTIONALLY SUBSTITUTED WITH E R2” S OR THE LIKE, R3 IS A HYDROGEN ATOM OR THE LIKE, X IS A SINGLE BOND OR -(CR6 R7 ), -, EACH OF R4 AND R5 IS INDEPENDENTLY C -C6 ALKYL OR THE LIKE, R6 AND R7 ARE HYDROGEN ATOMS OR CI -C6 ALKYL, R8 IS PHENYL, PHENYL OPTIONALLY SUBSTITUTED WITH K R8”S OR THE LIKE, A TAUTOMER OF THE COMPOUND OR A PHARMACEUTICALLY ACCEPTABLE SALT OR SOLVATE THEREOF, AS AN ACTIVE INGREDIENT.