The present invention discloses a low-cost, user-friendly and portable point-of-care system for detection of physical stress at different parts of body of a human subject. The prototype comprises a sensor arrangement, a processing unit, and a power supply. The sensor arrangement consists of a flexible and soft substrate preferably made of electrically conducting layer coated polymer facilitating detection of electric field potential of a part of a living body of the human subject such as finger-tip, tip-toe, wrist, or tongue, once they come in contact with said sensor arrangement. The sensor arrangement generates an electrical signal, which can be correlated to the stress level of the body parts at a very high-precision. The electrical signal generated by the sensor arrangement is sent to the processing unit, which may be further transmitted wirelessly to a mobile android application for the display of the results. The present system is useful for the early detection of many diseases or disorders related to heart, nerves and muscles, which can be correlated with the symptom of increase in the stress at different body parts such as finger-tip, tip-toe, wrist, or tongue, among others.
