WU, Wen-Lian,HE, Shuwen,WALSH, Shawn, P.,CUMMING, Jared, N.
申请号：
EP16740527
公开号：
EP3261442A4
申请日:
2016.01.15
申请国别(地区):
EP
年份:
2018
代理人:
摘要：
In its many embodiments, the present invention provides certain iminothiazine dioxide compounds, including compounds Formula (I): or a tautomers thereof, and pharmaceutically acceptable salts of said compounds and said tautomers, wherein R1, R2, ring A, RA, m, ringB, RB, and n are as defined herein. The novel compounds of the invention are useful as BACE inhibitors and/or for the treatment and prevention of various pathologies related thereto. Pharmaceutical compositions comprising one or more such compounds (alone and in combination with one or more other active agents), and methods for their preparation and use, including for the possible treatment of Alzheimers disease, are also disclosed.
