NAKAZATO, ATSURO,OKUBO, TAKETOSHI,NOZAWA, DAI,TAMITA, TOMOKO,KENNIS, LUDO E. J.
申请号：
CA2568804
公开号：
CA2568804C
申请日:
2005.06.24
申请国别(地区):
CA
年份:
2014
代理人:
摘要：
[PROBLEM TO BE SOLVED] An object of the present invention is to provide anantagonist against CRF receptors and/or an agonist for receptors which iseffective as a therapeutic or prophylactic agent for diseases in which CRF isconsidered to be involved, such as depression, anxiety, Alzheimer's disease,Parkinson's disease, Huntington's chorea, eating disorder, hypertension,gastrointestinal diseases, drug dependence, cerebral infarction, cerebralischemia, cerebral edema, cephalic external wound, inflammation, immunity-related diseases, alopecia, irritable bowel syndrome, sleep disorders,epilepsy, dermatitides, schizophrenia, pain, etc. [SOLUTION] Apyrrolopyrimidine or pyrrolopyridine derivative substituted with a cyclicamino group represented by the following formula [I] has a high affinity forCRF receptors and/or .delta. receptors, and is effective against diseases inwhich CRF is considered to be involved.
