The present invention provides for a novel oil-in-water (O/W) emulsion with increased stability in the presence of bacterial or viral suspensions especially those concentrated and non-purified (crude extracts) or minimally purified. The emulsion of the present invention can act as vehicle for the delivery of a pharmaceutical composition comprising at least one immunogen and in particular an immunogen selected from the group consisting of an inactivated pathogen an attenuated pathogen a subunit a recombinant expression vector and a plasmid or combinations thereof. Figure 1