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Pregnane steroids and their use in the treatment of CNS disorders
专利权人:
Torbjörn Bäckström;Ming-De Wang;Inga-Maj Johansson;Per Lundgren
发明人:
Torbjörn Bäckström,Per Lundgren,Ming-De Wang,Inga-Maj Johansson
申请号:
US12986937
公开号:
US08119619B2
申请日:
2011.01.07
申请国别(地区):
US
年份:
2012
代理人:
摘要:
Steroid compounds possessing a hydrogen donor in 3beta position, either in the form of a hydroxy- or a sulfate group, function as efficient blockers of the 3alpha-hydroxy-pregnan-steroid action and thus have utility as therapeutic substances for the prevention and/or treatment of steroid related CNS disorders. Treatment methods based on the administration of these substances are disclosed, and these substances either alone or in combination are also suggested for the manufacture of pharmaceuticals for the treatment of many specific steroid induced CNS disorders.
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