MESSEGUER PEYPOCH ANGEL,MOURE FERNANDEZ ALEJANDRA,GONZALEZ PINACHO DANIEL,MASIP MASIP ISABEL,PEREZ PAYA ENRIQUE,GARCIA VILLAR NATIVIDAD,MONLLEO MAS ESTER,CATENA RUIZ JUANLO
申请号：
NZ59812510
公开号：
NZ598125A
申请日:
2010.07.29
申请国别(地区):
NZ
年份:
2014
代理人:
摘要：
598125 Disclosed herein are 2,5-piperazinedione derivatives of formula (I) which inhibit apoptotic peptidase activating factor 1 (APAF-1), and consequently are useful as active pharmaceutical principles for the prophylaxis and/or treatment of a pathological and/or physiological condition associated with an increase in apoptosis. In one embodiment the derivative is 2- (4-(2,4-dichlorophenethyl)-1-(4-fluorobenzyl)-3,6-dioxopiperazin-2-yl) acetic acid.
