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Periostin induces proliferation of cardiomyocytes and promotes cardiac regeneration
专利权人:
Bernhard Kuhn
发明人:
Bernhard Kuhn
申请号:
US12524097
公开号:
US08936806B2
申请日:
2008.01.22
申请国别(地区):
US
年份:
2015
代理人:
摘要:
The present invention provides compositions and methods for increasing proliferation, increasing cell cycle activity, and/or proliferation of postmitotic mammalian differentiated cardiomyocytes. The invention can be used to slow, reduce, or prevent the onset of cardiac damage caused by, for example, myocardial ischemia, hypoxia, stroke, or myocardial infarction in vivo. In addition, the methods and compositions of the invention can be used to enhance proliferation of differentiated cardiomyocytes in vitro and/or ex vivo, which can then be used in tissue grafting.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/
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