The system and method of the present application includes an ECG acquisition device having a USB connector for connecting the device to a host device and a patient connector for connecting the device to a patient with ECG leads. The ECG acquisition device of the present system further includes a processor and storage medium, a power management and brokering module, a USB communications control module, an ECG acquisition circuit, and a patient isolation module. Unlike prior art ECG acquisition systems, the system of the present application affords a truly portable ECG acquisition device that may be connected through the USB connector to any host device having software processing capabilities and a display. The ECG acquisition device auto-loads and runs ECG monitoring software onto the host device eliminating the need to install additional acquisition software and/or drivers to the host device, and allows the acquisition device to interface with a host device of varying platforms.
