MCWHIRTER, John,GURER, Cagan,MACDONALD, Lynn,MURPHY, Andrew J.
申请号:
EP20140835599
公开号:
EP3071025(B1)
申请日:
2014.11.10
申请国别(地区):
欧洲专利局
年份:
2018
代理人:
摘要:
Non-human animals, cells, methods and compositions for making and using the same are provided, wherein the non-human animals and cells comprise a humanized a proliferation-inducing ligand gene. Non-human animals and cells that express a human or humanized a proliferation-inducing ligand protein from an endogenous a proliferation-inducing ligand locus are described.