Mark L. Boys;James B. Kramer;Stephen D. Barrett;Huifen Chen
发明人:
Stephen D. Barrett,James B. Kramer,Mark L. Boys,Huifen Chen
申请号:
US13112520
公开号:
US08455512B2
申请日:
2011.05.20
申请国别(地区):
US
年份:
2013
代理人:
摘要:
The present invention provides for compounds of Formula I, and pharmaceutically acceptable salts thereof,wherein R1, R2, R3, R4, R5, R6, and R7 have any of the values defined therefore in the specification, and pharmaceutically acceptable salts thereof, that are useful as therapeutic agents in the treatment of TGFβ-mediated conditions, including cancer and fibrotic disorders. Also provided are pharmaceutical compositions comprising one or more compounds of Formula I.