HERDEWIJN, PIET,DE JONGHE, STEVEN,GAO, LING-JIE,JANG, MI-YEON,VANDERHOYDONCK, BART,WAER, MARK JOZEF ALBERT,LIN, YUAN,HERMAN, JEAN FERDINAND,LOUAT, THIERRY ANDRE MICHEL
申请号：
CA2754890
公开号：
CA2754890C
申请日:
2010.03.15
申请国别(地区):
CA
年份:
2018
代理人:
摘要：
The present invention relates to compound of formula I, II, III, or IV, and/ora pharmaceutical acceptable additionsalt thereof and/or a stereoisomer thereof and/or a solvate thereof, whereinR1, R2, R3, R4, R5, R6, R7, R8, R9, R11, and R12 are as definedin the claim 1. The present invention also relates to a method for theirpreparation, as well as to pharmaceutical compositionsthereof. The present invention further relates to the use of said compounds asbiologically active ingredients, more specificallyas medicaments for the treatment of disorders and pathologic conditions suchas, but not limited to, immune and auto-immunedisorders, organ and cells transplant rejections.
