PROBLEM TO BE SOLVED: To develop a production inhibiting agent for carboxymethyl arginine accumulating specifically in collagen, and provide a composition and a method in which the agent can be effectively utilized.SOLUTION: A carboxymethyl arginine production inhibiting agent includes aqueous extract of Camellia seeds as an active ingredient. There is also provided an oral composition or a skin external preparation in which the agent is blended. There is also provided a skin cosmetic method in which the extract or agent is ingested or applied to the skin.COPYRIGHT: (C)2014,JPO&INPIT【課題】コラーゲンに特異的に蓄積するカルボキシメチルアルギニンの生成阻害剤を開発し、該剤を有効活用することができる組成物や方法を提供する。【解決手段】ツバキ種子の水性抽出物を有効成分としてなるカルボキシメチルアルギニン生成阻害剤。該剤を配合してなる経口組成物又は皮膚外用剤。前記抽出物又は剤を経口摂取又は皮膚へ適用する皮膚美容方法。【選択図】なし