Universitat Pompeu-Fabra;CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS;Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria (INIA)
发明人:
申请号：
EP12382135.7
公开号：
EP2647390A1
申请日:
2012.04.02
申请国别(地区):
EP
年份:
2013
代理人:
摘要：
The invention relates to a dendrimeric peptide construct of formula (I) wherein: T is a T epitope of the FMDV, bound to the lysine core by its N-terminal end, B is a B epitope of the FMDV, W is a linker group, Z is Cys bound to the linker group W through its sulphur atom or Lys bound to the linker group W through its ε amino group, X is absent when B is bound to the α-carboxylic group of Z by its N-terminal end or is an acyl group when B is bound to the α-amino group of Z by its C-terminal end. The invention also refers to the use of said constructs as an immunogen for the prevention of foot-and-mouth disease in an animal.
