MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH;SUMMA HEALTH SYSTEM
发明人:
Jamison James M.,Miller Thomas M.,Mcguire Karen M.,Masyuk Tetyana V.,Larusso Nicholas F.
申请号：
NZ63074614
公开号：
NZ630746A
申请日:
2014.01.10
申请国别(地区):
NZ
年份:
2017
代理人:
摘要：
Disclosed herein is the use of a therapeutically effective amount of a synergistic combination of (i) vitamin C, or a pharmaceutically acceptable salt, solvate, or hydrate thereof； and (ii) vitamin K, or a single enantiomer, a mixture of enantiomers, or a mixture of diastereomers thereof, or a pharmaceutically acceptable salt, solvate, or hydrate thereof in the manufacture of a medicament for treating, preventing, or ameliorating a polycystic disease； wherein the polycystic disease is a polycystic kidney disease caused by a mutation in PKD1, PKD2, or PKD3； an autosomal recessive polycystic kidney disease； a polycystic kidney disease caused by a mutation in PKHD1； a polycystic liver disease caused by a mutation in PPRKCSH or SEC63； a polycystic pancreas disease； or a polycystic ovarian syndrome.
