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Targeted Therapies for Cancer
专利权人:
发明人:
Mitesh Jivraj Borad,David Craig,John Carpten
申请号:
US15666493
公开号:
US20180125846A1
申请日:
2017.08.01
申请国别(地区):
US
年份:
2018
代理人:
摘要:
Methods of treating, and for selecting a chemotherapy regimen for treatment of cancer in a patient (FIG. 9). For example, a patient genetic sample from a bilary cancer such as cholangiocarcinoma is analyzed for a mutation in ERRFII and a chemotherapeutic agent is selected as a result of the analysis. If a mutation in ERRFII is present, treatment with an inhibitor of Epidermal Growth Factor Receptor (EGFR) is shown to have inhibitory effects on tumor growth. In this manner, the chemotherapy regimen is targeted to a given mutation in a patients cancer.
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