The present invention relates to a pharmaceutical composition comprising at least one liposome, at least one polyvalent counterion donor or a pharmaceutically acceptable salt thereof, at least one monovalent counterion donor or a pharmaceutically acceptable salt thereof, and an amphipathic therapeutic agent. The present invention also relates to methods of inhibiting cancer cell growth, comprising administering the pharmaceutical composition described herein.本發明係關於一種用於控制藥物釋放特性的醫藥組合物,其包含至少一種脂質體、至少一種多價相對離子供體或其醫藥學上可接受之鹽、至少一種單價相對離子供體或其醫藥學上可接受之鹽及兩性治療劑。本發明亦關於所述之醫藥組合物用於製造抑制癌細胞生長之醫藥品的用途,其包含治療有效劑量的所述之醫藥組合物。