Francesc CARRERA CARRERA,Juan Bautista PEREZ GARCIA,Bernat VIDAL JUAN,Francisco SANCHEZ IZQUIEROD,Maria Carme SERRA COMA
申请号:
US15313762
公开号:
US20170158699A1
申请日:
2015.05.21
申请国别(地区):
US
年份:
2017
代理人:
摘要:
The present invention is directed to novel pharmaceutically acceptable, addition salts of (S)-2-(1-(6-amino-5-cyanopyrimidin-4-ylamino)ethyl)-4-oxo-3-phenyl-3,4-dihydropyrrolo[1,2-f][1,2,4]triazine-5-carbonitrile with sulfonic acid derivatives, in particular with methanesulfonic acid, naphthalene-2-sulfonic acid and para-toluenesulfonic acid, and pharmaceutically acceptable solvates thereof, and their use as Phosphoinositide 3-Kinase (PI3K) inhibitors.