TAKEDA PHARMACEUTICAL COMPANY LIMITED;JENKINS Richard;HIBBERD Mark
发明人:
JENKINS Richard,HIBBERD Mark
申请号：
IL25441917
公开号：
IL254419D0
申请日:
2017.09.11
申请国别(地区):
IL
年份:
2017
代理人:
摘要：
The invention provides a potassium-competitive acid blocker (P-CAB) for use in the treatment, prevention and/or reduction of gastro-esophageal reflux disease (GERD) symptoms in patients who are partial responders to a proton pump inhibitor (PPI). The P-CAB may, for example, be selected from 1-[5-(2-fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrol-3-yl]-N-methylmethanamine (vonoprazan), revaprazan (YH1855), YH4808, RQ-4 and CS-526, or a salt thereof.
