Jiang Ding;Julio C. Spinelli;Jeffrey E. Stahmann;Yinghong Yu
发明人:
Jiang Ding,Yinghong Yu,Julio C. Spinelli,Jeffrey E. Stahmann
申请号：
US12254631
公开号：
US08295927B2
申请日:
2008.10.20
申请国别(地区):
US
年份:
2012
代理人:
摘要：
This document discusses, among other things, systems, devices, and methods measure an impedance and, in response, adjust an atrioventricular (AV) delay or other cardiac resynchronization therapy (CRT) parameter that synchronizes left and right ventricular contractions. A first example uses parameterizes a first ventricular volume against a second ventricular volume during a cardiac cycle, using a loop area to create a synchronization fraction (SF). The CRT parameter is adjusted in closed-loop fashion to increase the SF. A second example measures a septal-freewall phase difference (PD), and adjusts a CRT parameter to decrease the PD. A third example measures a peak-to-peak volume or maximum rate of change in ventricular volume, and adjusts a CRT parameter to increase the peak-to-peak volume or maximum rate of change in the ventricular volume.
