Andrew G. Myers,David A. Kummer,Derun Li,Evan Hecker,Amelie Dion,Peter M. Wright
申请号：
US13266788
公开号：
US20120115818A1
申请日:
2010.04.30
申请国别(地区):
US
年份:
2012
代理人:
摘要：
Efficient method for preparing the enone intermediate (VII) used in the synthesis of tetracyclines derivatives. In particular, the invention provides a synthesis which allows for substituents at positions 4a, 5, 5a, and 12a of the tetracycline ring system.
