Guiding catheter comprising a first end and a second end, and at least three main portions being: a first linear portion connected to the first end, a second curved portion connected to the first linear portion, a third linear portion, connected to the second curved portion, opposite to the first linear portion, and connected to said second end, characterized in that said second curved portion subtends an angle β from 195° to 240° and in that said third linear portion is provided to engage an active distal tip as fourth portion.