Selective reduction and derivatization of engineered proteins comprising at least one non-native cysteine

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专利权人:

Henrik Ostergaard

发明人:

Henrik Ostergaard,Anders Klarskov Petersen

申请号：

US11917772

公开号：

US08633300B2

申请日:

2006.06.19

申请国别(地区):

US

年份:

2014

代理人:

摘要：

The present invention relates to method for selective reduction and derivatization of recombinantly prepared engineered proteins comprising at least one non-native cysteine, wherein the reduction reaction is conducted in the presence of a redox buffer or in the presence of a triarylphosphine reducing agent.

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