Yat Sun Or,Brett Granger,Ruichao Shen,Xuechao Xing,Bin Wang,Jun Ma,Jing He,Jiang Long,Yong He,Guoqiang Wang
申请号:
US15497268
公开号:
US10080741B2
申请日:
2017.04.26
申请国别(地区):
US
年份:
2018
代理人:
摘要:
The present invention provides compounds of Formula I:pharmaceutical compositions comprising these compounds and methods of using these compounds to treat or prevent a disease or disorder mediated as FXR modulators. Specifically, the present invention relates to isoxazole derivatives useful as agonists for FXR, and methods for their preparation and use.