Embodiments described herein generally relate to an apparatus and methods for preventing the recontamination of a pathogen-reduced fluid by pathogens trapped in one or more ports of an inactivation fluid container. Through the use of a slidable clamp positioned in an area of the container immediately adjacent to a port to be isolated, the port may be sealed to prevent any liquid product from entering the port and associated tubing when liquid product is added to the container. The slidable clamp includes a slot, in which the distal end of the slot has a larger width than the proximal end of the slot. The width of the slot at the narrowest, most proximal portion allows for a fluid-tight seal to be created when the slidable clamp is slid into the closed position with respect to the port to be isolated.
