COMPOSÉS ANTIMICROBIENS STÉROÏDES CATIONIQUES ET PROCÉDÉS DE FABRICATION DE TELS COMPOSÉS

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专利权人:

Brigham Young University

发明人:

SAVAGE, Paul, B.

申请号：

EP16796914

公开号：

EP3297633A4

申请日:

2016.05.03

申请国别(地区):

EP

年份:

2018

代理人:

摘要：

Cationic steroidal antimicrobial (CSA) compounds having amide functionality and methods of manufacturing such CSA compounds. The CSA compound can be a compound of Formula (I), Formula (II), Formula (III), or a salt thereof: where R18 has the following structure: -R20-(C=0)-N-R21R22 R20 is omitted or substituted or unsubstituted alkyl, alkenyl, alkynyl, or aryl, and R21 and R22 are independently selected from hydrogen, substituted or unsubstituted alkyl, substituted or unsubstituted alkenyl, substituted or unsubstituted alkynyl, or substituted or unsubstituted aryl, provided that at least one of R21 and R22 is not hydrogen.

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