MASSACHUSETTS INSTITUTE OF TECHNOLOGY;THE BRIGHAM AND WOMENS HOSPITAL;THE BRIGHAM AND WOMEN'S HOSPITAL, INC; INC
发明人:
FAROKHZAD, OMID C.,CHENG, JIANJUN,TEPLEY, BENJAMIN A.,LANGER, ROBERT S.,ZALE, STEPHEN E.
申请号:
CA2648099
公开号:
CA2648099C
申请日:
2007.03.30
申请国别(地区):
CA
年份:
2012
代理人:
摘要:
The present invention provides a drug delivery system for targeted delivery of therapeutic agent-containing particles to tissues, cells, and intracellular compartments. The invention provides targeted particles comprising a particle, one or more targeting moieties, and one or more therapeutic agents to be delivered and pharmaceutical compositions comprising inventive targeted particles. The present invention provides methods of designing, manufacturing, and using inventive targeted particles and pharmaceutical compositions thereof.