Christoph Heusser;Eveline Schaadt;Marta Cosenza;Julia Neugebauer;Stefanie Urlinger;Maximilian Woisetschlaeger
发明人:
Marta Cosenza,Christoph Heusser,Julia Neugebauer,Eveline Schaadt,Stefanie Urlinger,Maximilian Woisetschlaeger
申请号：
US13991984
公开号：
US09458240B2
申请日:
2011.12.08
申请国别(地区):
US
年份:
2016
代理人:
摘要：
Anti-BAFFR antibodies are formulated as lyophilisate or liquid formulation. The lyophilisates can be reconstituted to give a solution with a high concentration of the antibody active ingredient for delivery to a patient without high levels of antibody aggregation. The lyophilisate can be reconstituted with an aqueous reconstituent to provide an aqueous composition in which the antibody has a concentration of at least 50 mg/ml. The lyophilisate or aqueous pharmaceutical composition may include one or more of a sugar, a buffering agent, a surfactant, and/or a free amino acid.
